Short Leukocyte Telomere Length is Associated with Abdominal Aortic Aneurysm (AAA)
نویسندگان
چکیده
منابع مشابه
Short leukocyte telomere length is associated with aortic dissection.
BACKGROUND Aortic dissection is an age-related and lethal vascular disease. Aging, which is associated with degeneration, is the major risk factor of aortic dissection. Telomeres are specialized DNA structures located at the end of eukaryotic chromosomes, the telomere length could be considered as an index of vascular aging. The purpose of present study was undertaken to investigate the relatio...
متن کاملIs Leukocyte Telomere Length Related with Lung Cancer Risk?: A Meta-Analysis
Background: Epidemiological studies have probed the correlation between telomere length and the risk of lung cancer, but their findings are inconsistent in this regard. The present meta-analysis study has been carried out to demonstrate the association between relative telomere length in peripheral blood leukocytes and the risk of lung cancer using an established Q-PCR technique. Methods:...
متن کاملChildhood Obesity Is Associated with Shorter Leukocyte Telomere Length
CONTEXT Obesity in adults is associated with shorter mean leukocyte telomere length (LTL), a marker of biological age that is also associated with age-related conditions including cardiovascular disease and type 2 diabetes. However, studies of childhood obesity and LTL have proved inconclusive. OBJECTIVE The objective of the study was to clarify the relationship between telomere length and ch...
متن کاملLeukocyte telomere length is associated with measures of subclinical atherosclerosis.
AIMS Our aim was to test the association of mean leukocyte telomere length (LTL) with ultrasonic measures of subclinical atherosclerosis such as intima-media thickness in the common carotid (IMTcc) and sum of plaque areas (SPA) and with serological markers. METHODS AND RESULTS Carotid and femoral bifurcations were scanned in 762 general population volunteers (46% men) over 40. Four features w...
متن کاملDrug addiction is associated with leukocyte telomere length
Telomeres are protective chromosomal structures that play a key role in preserving genomic stability. Telomere length is known to be associated with ageing and age-related diseases. To study the impairment of telomeres induced by drug abuse, we conducted an association study in the Chinese Han population. Multivariate linear regression analyses were performed to evaluate the correlation of leuk...
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ژورنال
عنوان ژورنال: European Journal of Vascular and Endovascular Surgery
سال: 2010
ISSN: 1078-5884
DOI: 10.1016/j.ejvs.2010.01.013